Clinical laboratory requirements

Clinical laboratories rely on precise and accurate test results, which depend heavily on high-quality Reverse Osmosis and Deionization (RODI) water systems. These systems ensure that contaminants do not compromise test sensitivity and specificity. Particularly for detecting analytes like triglycerides at parts-per-trillion (ppt) levels, stringent system design and handling are essential.

Key Design Parameters for RODI Water Systems:

  • Velocity and Pressure: Maintaining proper velocity and pressure prevents contaminant buildup and ensures consistent water quality
  • Recirculation and Bacteria Control: Regular recirculation and UV sterilization minimize bacterial growth and contamination, preventing false positives
  • Temperature and Dissolved Oxygen Levels: Controlled temperature and low dissolved oxygen levels ensure reagent stability and prevent analyzer alarms

Addressing bacterial contamination is crucial, as elevated CO2 levels detected by analyzers may indicate bacteria in the RODI loop.

High purity water systems for CLRW

Atlas High Purity Water designs, installs, and services clinical laboratory water systems that meet or exceed CLRW (Clinical Laboratory Reagent Water) specifications. CLRW standards require water used in clinical laboratories to have extremely low levels of contaminants to ensure reliable and accurate test results. Key specifications include:

  • Bacterial Content: Must be less than 10 colony-forming units (CFU) per milliliter
  • Total Organic Carbon (TOC): Must be less than 500 parts per billion (ppb)
  • Resistivity: Must be greater than 10 megohms
  • Particulate Matter: Water must be filtered to 0.22 microns

Our systems feature:

  • Advanced Filtration and Deionization: Removes the smallest ionic and microbiological contaminants
  • Comprehensive Bacterial Control: UV sterilization and regular flushing
  • Precise Temperature and Oxygen Management: Ensuring stable, alarm-free analyzer operation

Atlas High Purity Water provides 24/7 emergency service support, ensuring minimal downtime and continuous operation for reliable test results.

RODI water systems are vital for the accuracy of clinical analyzers. By adhering to strict design and operational standards, Atlas High Purity Water supports laboratories in delivering precise, contamination-free results, contributing to better patient care.